Deshaies, Raymond J: search on Z-Library

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1

RING Domain E3 Ubiquitin Ligases

Deshaies, Raymond J., Joazeiro, Claudio A.P.

Journal:

Annual Review of Biochemistry

Year:

2009

Language:

english

File:

PDF, 935 KB

english, 2009

2

Protein degradation: Prime time for PROTACs

Deshaies, Raymond J

Journal:

Nature Chemical Biology

Year:

2015

Language:

english

File:

PDF, 1.04 MB

english, 2015

3

Corrigendum: Protein degradation: Prime time for PROTACs

Deshaies, Raymond J

Journal:

Nature Chemical Biology

Year:

2015

Language:

english

File:

PDF, 94 KB

english, 2015

4

Multispecific drugs herald a new era of biopharmaceutical innovation

Deshaies, Raymond J.

Journal:

Year:

2020

File:

PDF, 2.53 MB

2020

5

Cand1-Mediated Adaptive Exchange Mechanism Enables Variation in F-Box Protein Expression

Liu, Xing, Reitsma, Justin M., Mamrosh, Jennifer L., Zhang, Yaru, Straube, Ronny, Deshaies, Raymond J.

Journal:

Year:

2018

Language:

english

File:

PDF, 3.10 MB

english, 2018

6

Discovery of an Inhibitor of the Proteasome Subunit Rpn11

Perez, Christian, Li, Jing, Parlati, Francesco, Rouffet, Matthieu, Ma, Yuyong, Mackinnon, Andrew L., Chou, Tsui-Fen, Deshaies, Raymond J., Cohen, Seth M.

Journal:

Journal of Medicinal Chemistry

Year:

2017

Language:

english

File:

PDF, 1.45 MB

english, 2017

7

Tag Team Ubiquitin Ligases

Kleiger, Gary, Deshaies, Raymond

Journal:

Year:

2016

Language:

english

File:

PDF, 250 KB

english, 2016

8

Multiubiquitin Chain Receptors Define a Layer of Substrate Selectivity in the Ubiquitin-Proteasome System

Rati Verma, Robert Oania, Johannes Graumann, Raymond J Deshaies

Journal:

Year:

2004

Language:

english

File:

PDF, 479 KB

english, 2004

9

Selective Degradation of Ubiquitinated Sic1 by Purified 26S Proteasome Yields Active S Phase Cyclin-Cdk

Rati Verma, Hayes McDonald, John R Yates III, Raymond J Deshaies

Journal:

Year:

2001

Language:

english

File:

PDF, 283 KB

english, 2001

10

Exercising self-restraint: Discouraging illicit acts of S and M in eukaryotes

Joachim J. Li, Raymond J. Deshaies

Journal:

Year:

1993

Language:

english

File:

PDF, 428 KB

english, 1993

11

NEDD8 links cullin-RING ubiquitin ligase function to the p97 pathway

Besten, Willem den, Verma, Rati, Kleiger, Gary, Oania, Robert S, Deshaies, Raymond J

Journal:

Nature Structural and Molecular Biology

Year:

2012

Language:

english

File:

PDF, 778 KB

english, 2012

12

LO45: Simulation-based research in emergency medicine in Canada: priorities and perspectives

Chaplin, T., Thoma, B., Petrosoniak, A., Caners, K., McColl, T., Forristal, C., Dakin, C., Deshaies, J., Raymond-Dufresne, E., Fotheringham, M., Ha, D., Holm, N., Huffman, J., Lonergan, A., Mastoras,

Journal:

Year:

2019

Language:

english

File:

PDF, 67 KB

english, 2019

13

Editorial overview: Cell multiplication

Raymond J Deshaies, Martin Eilers

Journal:

Current Opinion in Cell Biology

Year:

2001

Language:

english

File:

PDF, 39 KB

english, 2001

14

COP9 Signalosome: A Multifunctional Regulator of SCF and Other Cullin-Based Ubiquitin Ligases

Gregory A Cope, Raymond J Deshaies

Journal:

Year:

2003

Language:

english

File:

PDF, 348 KB

english, 2003

15

Proteotoxic crisis, the ubiquitin-proteasome system, and cancer therapy

Deshaies, Raymond J

Journal:

Year:

2014

Language:

english

File:

PDF, 2.20 MB

english, 2014

16

Epidithiodiketopiperazines Inhibit Protein Degradation by Targeting Proteasome Deubiquitinase Rpn11

Li, Jing, Zhang, Yaru, Da Silva Sil Dos Santos, Bruno, Wang, Feng, Ma, Yuyong, Perez, Christian, Yang, Yanling, Peng, Junmin, Cohen, Seth M., Chou, Tsui-Fen, Hilton, Stephen T., Deshaies, Raymond J.

Journal:

Cell Chemical Biology

Year:

2018

File:

PDF, 2.53 MB

2018

17

Diverse roles for ubiquitin-dependent proteolysis in transcriptional activation

Lipford, J. Russell, Deshaies, Raymond J.

Journal:

Nature Cell Biology

Year:

2003

Language:

english

File:

PDF, 190 KB

english, 2003

18

Cdc48/p97 Mediates UV-Dependent Turnover of RNA Pol II

Rati Verma, Robert Oania, Ruihua Fang, Geoffrey T. Smith, Raymond J. Deshaies

Journal:

Year:

2011

Language:

english

File:

PDF, 1.25 MB

english, 2011

19

Multisite Phosphorylation and the Countdown to S Phase

Raymond J. Deshaies, James E. Ferrell Jr.

Journal:

Year:

2001

Language:

english

File:

PDF, 185 KB

english, 2001

20

Physiologically relevant and portable tandem ubiquitin-binding domain stabilizes polyubiquitylated proteins

An Tyrrell, Karin Flick, Gary Kleiger, Hongwei Zhang, Raymond J. Deshaies, Peter Kaiser and Alexander Varshavsky

Journal:

Proceedings of the National Academy of Sciences

Year:

2010

Language:

english

File:

PDF, 1.29 MB

english, 2010

21

Gal4 turnover and transcription activation

Collins, Galen A., Lipford, J. Russell, Deshaies, Raymond J., Tansey, William P.

Journal:

Year:

2009

Language:

english

File:

PDF, 116 KB

english, 2009

22

Chfr is linked to tumour metastasis through the downregulation of HDAC1

Oh, Young Mi, Kwon, Young Eun, Kim, Joo Mi, Bae, Sung Jun, Lee, Bo Keun, Yoo, Soon Ji, Chung, Chin Ha, Deshaies, Raymond J., Seol, Jae Hong

Journal:

Nature Cell Biology

Year:

2009

Language:

english

File:

PDF, 2.02 MB

english, 2009

23

Valosin-containing protein (VCP)–Adaptor Interactions are Exceptionally Dynamic and Subject to Differential Modulation by a VCP Inhibitor

Xue, Liang, Blythe, Emily E., Freiberger, Elyse C., Mamrosh, Jennifer L., Hebert, Alexander S., Reitsma, Justin M., Hess, Sonja, Coon, Joshua J., Deshaies, Raymond J.

Journal:

Molecular & Cellular Proteomics

Year:

2016

Language:

english

File:

PDF, 3.23 MB

english, 2016

24

Increased proteasomal activity supports photoreceptor survival in inherited retinal degeneration

Lobanova, Ekaterina S., Finkelstein, Stella, Li, Jing, Travis, Amanda M., Hao, Ying, Klingeborn, Mikael, Skiba, Nikolai P., Deshaies, Raymond J., Arshavsky, Vadim Y.

Journal:

Nature Communications

Year:

2018

Language:

english

File:

PDF, 2.27 MB

english, 2018

25

Mutations in the Hydrophobic Core of Ubiquitin Differentially Affect Its Recognition by Receptor Proteins

Aydin Haririnia, Rati Verma, Nisha Purohit, Michael Z. Twarog, Raymond J. Deshaies, Dan Bolon, David Fushman

Journal:

Journal of Molecular Biology

Year:

2008

Language:

english

File:

PDF, 2.50 MB

english, 2008

26

A Proteasome Howdunit: The Case of the Missing Signal

Rati Verma, Raymond J Deshaies

Journal:

Year:

2000

Language:

english

File:

PDF, 71 KB

english, 2000

27

Assembly of yeast Sec proteins involved in translocation into the endoplasmic reticulum into a membrane-bound multisubunit complex

Deshaies, Raymond J., Sanders, Sylvia L., Feldheim, David A., Schekman, Randy

Journal:

Year:

1991

File:

PDF, 458 KB

1991

28

Genetic dissection of the early stages of protein secretion in yeast

Raymond J. Deshaies, François Kepes, Peter C. Böhni

Journal:

Trends in Genetics

Year:

1989

Language:

english

File:

PDF, 886 KB

english, 1989

29

Human CUL1 Forms an Evolutionarily Conserved Ubiquitin Ligase Complex (SCF) with SKP1 and an F-Box Protein

Svetlana A. Lyapina, Craig C. Correll, Edward T. Kipreos and Raymond J. Deshaies

Journal:

Proceedings of the National Academy of Sciences

Year:

1998

Language:

english

File:

PDF, 1.90 MB

english, 1998

30

Transcription Factor Nrf1 Mediates the Proteasome Recovery Pathway after Proteasome Inhibition in Mammalian Cells

Senthil K. Radhakrishnan, Candy S. Lee, Patrick Young, Anne Beskow, Jefferson Y. Chan, Raymond J. Deshaies

Journal:

Year:

2010

Language:

english

File:

PDF, 1.12 MB

english, 2010

31

Structure-Activity Relationship Study Reveals ML240 and ML241 as Potent and Selective Inhibitors of p97 ATPase

Chou, Tsui-Fen, Li, Kelin, Frankowski, Kevin J., Schoenen, Frank J., Deshaies, Raymond J.

Journal:

Year:

2013

Language:

english

File:

PDF, 2.00 MB

english, 2013

32

Click Chemistry Facilitates Formation of Reporter Ions and Simplified Synthesis of Amine-Reactive Multiplexed Isobaric Tags for Protein Quantification

Sohn, Chang Ho, Lee, J. Eugene, Sweredoski, Michael J., Graham, Robert L.J., Smith, Geoffrey T., Hess, Sonja, Czerwieniec, Gregg, Loo, Joseph A., Deshaies, Raymond J., Beauchamp, J. L.

Journal:

Journal of the American Chemical Society

Year:

2012

Language:

english

File:

PDF, 1.48 MB

english, 2012

33

Make it or break it: the role of ubiquitin-dependent proteolysis in cellular regulation

Raymond J. Deshaies

Journal:

Trends in Cell Biology

Year:

1995

Language:

english

File:

PDF, 1.37 MB

english, 1995

34

Development of p97 AAA ATPase inhibitors

Chou, Tsui-Fen, Deshaies, Raymond J.

Journal:

Year:

2011

Language:

english

File:

PDF, 446 KB

english, 2011

35

The role of stress proteins in membrane biogenesis

Deshaies, Raymond J., Koch, Bruce D., Schekman, Randy

Journal:

Trends in Biochemical Sciences

Year:

1988

Language:

english

File:

PDF, 803 KB

english, 1988

36

SEC11 Is Required for Signal Peptide Processing and Yeast Cell Growth

Peter C. Böhni, Raymond J. Deshaies and Randy W. Schekman

Journal:

The Journal of Cell Biology

Year:

1988

Language:

english

File:

PDF, 1.97 MB

english, 1988

37

Ubiquitin- and ATP-dependent unfoldase activity of P97/VCP•NPLOC4•UFD1L is enhanced by a mutation that causes multisystem proteinopathy

Blythe, Emily E., Olson, Kristine C., Chau, Vincent, Deshaies, Raymond J.

Journal:

Proceedings of the National Academy of Sciences

Year:

2017

Language:

english

File:

PDF, 1.19 MB

english, 2017

38

Cdc5 influences phosphorylation of Net1 and disassembly of the RENT complex

Wenying Shou, Ramzi Azzam, Susan L Chen, Michael J Huddleston, Christopher Baskerville, Harry Charbonneau, Roland S Annan, Steve A Carr, Raymond J Deshaies

Journal:

BMC Molecular Biology

Year:

2002

Language:

english

File:

PDF, 2.92 MB

english, 2002

39

Identification of a functional docking site in the Rpn1 LRR domain for the UBA-UBL domain protein Ddi1

Tara A Gomez, Natalie Kolawa, Marvin Gee, Michael J Sweredoski, Raymond J Deshaies

Journal:

Year:

2011

Language:

english

File:

PDF, 2.25 MB

english, 2011

40

Drug discovery: Fresh target for cancer therapy

Deshaies, Raymond J.

Journal:

Year:

2009

Language:

english

File:

PDF, 1.24 MB

english, 2009

41

Phosphorylation and proteolysis: partners in the regulation of cell division in budding yeast

Raymond J Deshaies

Journal:

Current Opinion in Genetics & Development

Year:

1997

Language:

english

File:

PDF, 1.93 MB

english, 1997

42

G1Cyclin-Dependent Activation of p34CDC28(Cdc28p) in vitro

Raymond J. Deshaies and Marc Kirschner

Journal:

Proceedings of the National Academy of Sciences

Year:

1995

Language:

english

File:

PDF, 1.13 MB

english, 1995

43

Degradation of the Deubiquitinating Enzyme USP33 Is Mediated by p97 and the Ubiquitin Ligase HERC2

Chan, Nickie C., den Besten, Willem, Sweredoski, Michael J., Hess, Sonja, Deshaies, Raymond J., Chan, David C.

Journal:

Journal of Biological Chemistry

Year:

2014

Language:

english

File:

PDF, 1.98 MB

english, 2014

44

Chemical Genetic Control of Protein Levels: Selective in Vivo Targeted Degradation

Schneekloth,, John S., Fonseca, Fabiana N., Koldobskiy, Michael, Mandal, Amit, Deshaies, Raymond, Sakamoto, Kathleen, Crews, Craig M.

Journal:

Journal of the American Chemical Society

Year:

2004

Language:

english

File:

PDF, 505 KB

english, 2004

45

The pseudophosphatase STYX targets the F‐box of FBXW7 and inhibits SCF FBXW7 function

Reiterer, Veronika, Figueras‐Puig, Cristina, Le Guerroue, Francois, Confalonieri, Stefano, Vecchi, Manuela, Jalapothu, Dasaradha, Kanse, Sandip M, Deshaies, Raymond J, Di Fiore, Pier Paolo, Behrends,

Journal:

The EMBO Journal

Year:

2017

Language:

english

File:

PDF, 2.45 MB

english, 2017

46

A subfamily of stress proteins facilitates translocation of secretory and mitochondrial precursor polypeptides

Deshaies, Raymond J., Koch, Bruce D., Werner-Washburne, Margaret, Craig, Elizabeth A., Schekman, Randy

Journal:

Year:

1988

File:

PDF, 737 KB

1988

47

The self-destructive personality of a cell cycle in transition

Raymond J Deshaies

Journal:

Current Opinion in Cell Biology

Year:

1995

Language:

english

File:

PDF, 1.17 MB

english, 1995

48

p97/VCP promotes degradation of CRBN substrate glutamine synthetase and neosubstrates

Nguyen, Thang Van, Li, Jing, Lu, Chin-Chun (Jean), Mamrosh, Jennifer L., Lu, Gang, Cathers, Brian E., Deshaies, Raymond J.

Journal:

Proceedings of the National Academy of Sciences

Year:

2017

Language:

english

File:

PDF, 1.12 MB

english, 2017

49

A putative stimulatory role for activator turnover in gene expression

Lipford, J. Russell, Smith, Geoffrey T., Chi, Yong, Deshaies, Raymond J.

Journal:

Year:

2005

Language:

english

File:

PDF, 389 KB

english, 2005

50

Cell multiplication: Peering in and peering out: regulation of and by the cell cycle

Raymond J Deshaies, Tyler Jacks

Journal:

Current Opinion in Cell Biology

Year:

1999

Language:

english

File:

PDF, 57 KB

english, 1999

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